What’s the Best Cream for Pimples? 5 Most Effective Anti Pimple Creams

Pimple spot treatments are great for quickly ridding yourself of one or two pesky pimples. But what about when you have clusters of breakouts or active, cystic acne? You need an effective lotion or cream for pimples that treats the entire area (or your whole face) – without irritating your skin.

While strong, harsh and potentially irritating ingredients like Benzoyl Peroxide can be great when you’re spot treating a zit or two, when you’re dealing with breakouts that cover bigger portions of your face, you want to choose an anti pimple cream that fights blemishes without irritating the rest of your skin.

After all, drying out and irritating your skin can actually lead to more oil production, clogged pores and blemishes. And ain’t nobody got time for that.

So if you’re looking to clear your face immediately and keep it blemish-free, here are the best gels, lotions and creams for pimples to get you to clearer days!

Dermalogica Overnight Clearing Gel

Dermalogica Overnight Clearing Gel (1.7 Fl Oz) Acne Treatment Gel with Salicylic Acid and Hyaluronic...
  • Helps remove impaction plugs from the follicle
  • Relieve congestion and prevent breakouts
  • Inhibits overactive sebaceous activity and purifies to promote skin clarity
While you sleep, your skin naturally heals and repairs itself. So it just makes sense to take full advantage of this deep repair by adding in an overnight pimple treatment.

And you can’t go wrong with Dermalogica’s Overnight Clearing Gel – this lightweight formula uses some of the most effective pimple fighting, pore clearing ingredients like Salicylic acid, Tea tree oil and Camphor and combines them with skin-soothers like Biotin and Niacinamide.

The result is a highly effective gel that won’t dry out or irritate even sensitive skin. Oh, and you don’t have to use it only at nighttime – it works great under makeup as a light lotion. Just make sure to wear sunscreen since salicylic acid can increase sun sensitivity.

Mario Badescu Buffering Lotion

Mario Badescu Buffering Lotion, 1 Fl Oz
  • Helps absorb excess oil
  • Helps reduce size of deep under-the-surface bumps
  • Lightweight, liquid formula

We love Mario Badescu’s whole line of blemish-fighting products but this Buffering Lotion particularly stands out. It’s formulated with nourishing B vitamins and amino acids to support overall healthy skin as well as anti-pimple ingredients like Zinc oxide.

Niacinamide, allantoin and other anti-inflammatory herbal extracts also do their part to ​soothe irritated skin and reduce redness.

But our favorite thing about this anti-pimple lotion? You can feel it sinking deep into your skin to get rid of the gunk and bacteria that make cystic pimples form in the first place. It’s one of the most effective pimple lotions for cystic acne so if you’re struggling from a breakout – get your hands face on a bottle!

Retinol Cream for Pimples

LilyAna Naturals Retinol Cream for Face - Retinol Cream, Anti Aging Cream, Retinol Moisturizer for...
  • Advanced Anti-Aging. Maximum strength Retinol formula delivers lifting, brightening,...
  • High Potency Results. Infused with a carefully balanced blend of highly effective...
  • Triple Duty Beauty Benefits. With a lightweight texture and zero residue, Retinol...

You probably already know that retinols are a must have to combat signs of aging like fine lines and wrinkles, but did you know that retinols are also amazing at getting rid of pimples?

Retinols are basically a form of vitamin A that works on your skin to increase cell turnover, making it harder for oil to block pores and create pimples. ​And it’s not just the stray pimple or two that retinol is effective for – a good retinol cream can treat and prevent everything from a random zit to stubborn cystic acne.

But that’s not all it does. In addition to promoting cell turnover, retinols also stimulate collage and elastin production. The result? You’ll notice less fine lines, fading dark spots and acne scars and overall glowing, rejuvenated skin.

Hard to believe one little ingredient can do all that but you’ll just have to try it to know it’s true.

Acnedote Oil Control Lotion

Alba Botanica Acnedote Maximum Strength Oil Control Lotion, 2 Oz
  • One 2 oz. tube of Alba Botanica Acnedote Maximum Strength Oil Control Lotion
  • Treats and prevents acne and breakouts
  • Made with a 2% salicylic acid and willow bark solution

Looking for a gentle, oil-free moisturizer that you can wear to fight pimples all day, every day? Look no further than Alba Botanical’s Acnedote.

This 100% vegetarian, oil-free ​lotion is gentle enough for the most sensitive skin. It contains no parabens, synthetic fragrances or other nasties that might irritate your skin – instead, it uses soothing, skin-strengthening botanicals like aloe vera, willow bark extract, nettle extract camellia sinensis leaf extract to reduce inflammation and keep your skin soft, clear and smooth.

The best part? It’s packing a serious pore-clearing ingredient: 2% Salicylic acid​. This famous beta-hydroxy acid (BHA) is oil soluble and unbeatable when it comes to getting deep into your pores to “de-gunk” what’s inside.

​This is hands down the most gentle daily lotion to both get rid of pimples and prevent future pimples from happening!

Tea Tree Oil Pimple Cream

Era Organics Tea Tree Oil Face Cream - For Oily, Acne Prone Skin, Extra Soothing & Nourishing...
  • Using Tea Tree Oil for acne is a centuries old natural remedy that still works today....
  • Extra Strength Nourishing Formula. Most acne treatments are too harsh on the skin,...
  • Ingredients Your Skin Will Love. We combine powerful botanical, food grade...

Having pimples is bad enough but what do you do when you’ve got pimples and dry skin? It’s not an easy combination especially since most pimple products contain ingredients that further dry out your skin. And the last thing you want is a dehydrated, painful face just to get rid of some zits.

​Meet Keeva Organic’s Acne Treatment Cream. This pimple cream is super moisturizing and perfect for healing dry, irritated skin. But in case you’re thinking it’ll make you break out even more – don’t worry, it wont.

Instead of heavy, pore-clogging ingredients, this Acne Treatment Cream uses natural butters and oils like shea butter, argan oil and rosehip seed oil (which is high in linoleic acid and one of the best oils for oily, acne-prone skin) to thoroughly nourish and hydrate your skin.

As for pesky pimples? ​It’s packing a potent blend of anti-inflammatory botanical extracts as well as pore-cleansing Salicylic acid and blemish-fighting Tea tree oil to zap zits without irritating the rest of your precious skin!

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